武磊
个人简历
科研成果
教学情况
研究方向
荣誉奖励
论文专著
个人简历
基本信息
职称:讲师
办公室地址:天演楼108
联系电话:18153627176
邮箱:leiwu@lzu.edu.cn
学习经历
2010/09-2015/06,兰州大学,5357cc拉斯维加斯线路通道,博士,导师:郭光沁
2007/09-2010/06,兰州大学,5357cc拉斯维加斯线路通道,硕士,导师:郭光沁
2003/09-2007/06,兰州大学,5357cc拉斯维加斯线路通道,本科
工作经历
2015/12-至今,兰州大学,5357cc拉斯维加斯线路通道,讲师
社会工作
科研成果
主持或参加的科研项目:
1. 国家自然科学基金面上项目,32271567,相分离介导组蛋白去乙酰化酶HDA6低温感受的机制研究,2023/01-2026/12,在研,参加
2. 甘肃省自然科学基金面上项目,22JR5RA462,CKRW1亚家族蛋白分子功能鉴定,2022/11-2024/10,在研,主持
3. 科技开发项目,LZUKYHT1118202210140506,高效表达腈水合酶的原核表达菌株开发,2022/10-2023/12,在研,主持
4. 国家自然科学基金面上项目,31970713,组蛋白H2B单泛素化修饰对植物内源生长素稳态的影响和作用机理,2020/01-2023/12,在研,参加
5. 甘肃省自然科学基金面上项目,20JR5RA270,CKRW2影响PIN2细胞定位的机理研究,2020/11-2022/10,已结题,参加
6. 中央高校优秀青年教师科研创新项目,Lzujbky-2020-33,泛素连接酶CKRW1家族参与根向重力响应研究,2020/01-2021/12,已结题,主持
7. 细胞活动与逆境适应教育部重点实验室开放项目,lzujbky-2019-kb05,CKRW1蛋白家族的功能研究,2019/07-2020/06,已结题,主持
8. 国家自然科学基金青年科学基金项目,31700215,拟南芥D53-like SMXLs调控植物盐耐受性的机制研究,2018/01-2020/12,已结题,参加
9. 国家自然科学基金青年科学基金项目,31600218,拟南芥CKRW1调节内源生长素水平稳态平衡的分子机理研究,2017/01-2019/12,已结题,主持
10. 国家自然科学基金面上项目,31671458,CKRC3在维持拟南芥内源生长素稳态中的作用和机理,2017/01-2020/12,已结题,参加
11. 中央高校自由探索项目,Lzujbky-2016-78,拟南芥CKRW1参与根向地性反应的分子机制,2016/01-2018/04,已结题,主持
12. 国家自然科学基金面上项目,31371431,酰基转移酶GFC1参与细胞分裂素信号转导的生化和分子机理,2014/01-2017/12,已结题,参加
13. 国家自然科学基金重点项目,31030045,植物生长素合成及代谢缺陷突变体的系统筛选和研究,2011/01-2014/12,已结题,参加
教学情况
研究方向
1. 拟南芥蛋白CKRW1参与调控内源生长素稳态的分子机理
2. 组蛋白H2B单泛素化修饰调控内源生长素稳态的分子机理
荣誉奖项
论文专著
1. Liu HQ#, Pu ZX#, Di DW, Zou YJ, Guo YM, Wang JL, Zhang L, Tian P, Fei QH, Li XF, Khaskheli AJ, Wu L*, Guo GQ*. Significance of NatB-mediated N-terminal acetylation of auxin biosynthetic enzymes in maintaining auxin homeostasis in Arabidopsis thaliana. Commun Biol., 2022, 5(1): 1410.
2. Wang JL, Di DW, Luo P, Zhang L, Li XF, Guo GQ, Wu L*. The roles of epigenetic modifications in the regulation of auxin biosynthesis. Front. Plant Sci., 2022, 13: 959053.
3. Luo P#*, Di DW#*, Wu L, Yang J, Lu Y, Shi W. MicroRNAs Are Involved in Regulating Plant Development and Stress Response through Fine-Tuning of TIR1/AFB-Dependent Auxin Signaling. Int. J. Mol. Sci., 2022, 23(1): 510.
4. Wang JL, Liang LY, Lang N, Li YY, Guo W, Cui J, Zou YJ, Liu HQ, Fei QH, Li XF, Guo GQ, Wu L*. An improved plant CRISPR-Cas9 system for generating Cas9-free multiplex mutants. Biotechnol & Biotechnol Equipment, 2021, 35(1): 1850-1857
5. Lang N, Liang LY, Wang JL, Wu L*. CRISPR/Cas9-Enabled Multiplex Gene Editing in Plant Research. Fenzi Zhiwu Yuzhong (Molecular Plant Breeding), 2021, https://kns.cnki.net/kcms/detail/46.1068.S.20210722.1032.002.html
6. Liu HQ, Zou YJ, Li XF, Wu L, Guo GQ*. Stablization of ACOs by NatB mediated N-terminal acetylation is required for ethylene homeostasis. BMC Plant Biol., 2021, 21(1): 320
7. Wu L, Wang JL, Li XF, Guo GQ*. Cytokinin-Controlled Gradient Distribution of Auxin in Arabidopsis Root Tip. Int. J. Mol. Sci., 2021, 22(8): 3874
8. Zhang L, Luo P, Bai J, Wu L, Di DW, Liu HQ, Li JJ, Liu YL, Khaskheli AJ, Zhao CM*, Guo GQ*. Function of histone H2B monoubiquitination in Transcriptional regulation of auxin biosynthesis in Arabidopsis. Commun Biol., 2021, 4(1): 206
9. Zhang J, Hafeez MT, Di DW, Wu L, Zhang L*. Precise control of ABA signaling through post-translational protein modification. Plant Growth Regul., 2019, 88(2): 99–111
10. Fei QH, Zhang JH, Zhang ZR, Wang YX, Liang LY, Wu L, Gao HH, Sun YL, Niu BT, Li XF*. Effects of auxin and ethylene on root growth adaptation to different ambient temperatures in Arabidopsis. Plant Sci., 2019, 281: 159-172
11. Fei QH, Liang LY, Li F, Zhang L, Li YX, Guo YM, Wu L, Meng XQ, Gao HH*, Li XF*. Transcriptome profiling and phytohormone responses of Arabidopsis roots to different ambient temperatures. J. Plant Interact., 2019, 14(1): 314-323,
12. Wang L*, Yu DL, Zhang HW, He LY, Wu L. Ortho-topolin riboside induces apoptosis in Acute myeloid leukemia HL-60 cells. Mol. Cell Toxicol, 2016, 12: 159-166
13. Di DW, Wu L, Zhang L, An CW, Zhang TZ, Luo P, Gao HH, Kriechbaumer V, Guo GQ*. Functional roles of Arabidopsis CKRC2/YUCCA8 gene and the involvement of PIF4 in the regulation of auxin biosynthesis by cytokinin. Sci. Rep., 2016, 6, 36866
14. Di DW#*, Wu L#, Luo P, Zhang L, Zhang TZ, Sun X, Wei SD, An CW, Guo GQ. Analysis the role of Arabidopsis CKRC6/ASA1 in auxin and cytokinin biosynthesis. Journal of Plant Biology, 2016, 59(2): 162-171
15. Wu L#, Luo P#, Di DW#, Wang L, Wang M, Lu CK, Wei SD, Zhang L, Zhang TZ, Amakorová P, MrvkováM, NovákO, Guo GQ*. Forward genetic screen for auxin-deficient mutants by cytokinin. Sci. Rep., 2015. 5: 11923
16. Wu L#, Zhou ZY#, Zhang CG#, Chai J, Zhou Q, Wang L, Hirnerová E, Mrvková M, Novák O, Guo GQ*. Functional roles of three cutin biosynthetic acyltransferases in cytokinin responses and skotomorphogenesis. PLoS One, 2015, 10(3): e0121943
17. Wu L*, Di DW, Zhang D, Song B, Luo P, Guo GQ. Frequent problems and their resolutions by using thermal asymmetric interlaced PCR (TAIL-PCR) to clone genes in Arabidopsis T-DNA tagged mutants. Biotechnol & Biotechnol Equipment, 2015, 29(2): 260-267
18. Zhou ZY#, Zhang CG#, Wu L, Zhang CG, Chai J, Wang M, Jha A, Jia PF, Cui SJ, Yang M,Chen R*, Guo GQ*. 2011. Functional characterization of the CKRC1/TAA1 gene and dissection of hormonal actions in the Arabidopsis root. Plant J., 2011, 66(3): 516-527